A case of adult onset dissemınated juvenile xanthogranuloma

41 year old female patient was admitted to our clinic with papules all over her body. Lesions started 3 years ago on her face and they remained stabile until having a traffic accident 1 year ago. After accident and subsequently operation, the lesions began spreading on whole body. In her personal history, there were a surgical operation because of the accident and concurrently diagnosis of diabetes mellitus. In her family history there was nothing important. In dermatological examination, multiple yellowish-pink coloured, some dome-shaped, indurated papules were detected on her head, hairy skin, external auditory canal, pubis and upper torso (Figs 1 3). Routine laboratory tests were normal. Histopathological examination of the lesions showed histiocytic infiltration and multinuclear giant cells and actin, desmin, S100 and factor XIIIa stains were found negative whereas CD68 was positive (Figs 4a d). Based on clinical and histopathological findings, patient was diagnosed as JX. There were no pathological findings in ocular and respiratory examinations of the patient. The patient was followed because the lesions has possibility of spontaneous resolution. But, 6 months later, there were no regression in control examination. ABSTRACT